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Trevi Fountain

Trevi Fountain

Gardens of Vatican City

Gardens of Vatican City

Roman Forum

Roman Forum

Rome Colosseum

Rome Colosseum

Rome Skyline

Rome Skyline

San Pietro

San Pietro

Sistine Chapel

Sistine Chapel

Sistine Chapel

Sistine Chapel

Sistine Hall

Sistine Hall

The Sistine Hall of the Vatican Library

The Sistine Hall of the Vatican Library

Trevi Fountain

Trevi Fountain

Vatican Museum

Vatican Museum

Vatican Museum Staircase

Vatican Museum Staircase

View of Rome from the Vatican

View of Rome from the Vatican

Cruises From Rome: Your Gateway to Mediterranean Adventures

If Rome, Italy, isn't on your cruise vacation bucket list, you've either already been or simply forgotten to add it. Italy's capital city is a cultural destination with endless historical sites. It was once the center of the Roman Empire, and the unique history, captivating art, and architectural wonders you'll find here are well worth the trip. Rome is a great departure port for a cruise vacation, and at CruiseDirect, we have the best prices on scores of itineraries that begin in this beautiful city.

Every cruise from Rome should be bookended by sightseeing around the city. Visit the Vatican Museums, the Roman Forum, the Colosseum, the Pantheon, and St. Peter's Basilica. Art history lovers will find that time stops when they are standing underneath Michelangelo's Sistine Chapel ceiling! Rome's culinary scene is world-class, too, and the vibrant nightlife is also not to be missed, with live music and dance clubs found all throughout the city. Book cruises from Rome at the best price online and discover why they call it the Eternal City before you set sail!


 

  • Destination Port 1 Airport
  • Destination port 2 Departure port

Monthly Weather Averages

The graph that represents the temperature in fahrenheit
month graph
The graph that represents the precipitation rate forecast in inches
  • Temperature in Fahrenheit
  • Rain in Inches

Current Weather

Rome
48°F
Clear
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Saturday

51° 40°

Sunday

51° 37°

Monday

52° 39°

Tuesday

48° 35°

Cruise Lines That Offer Cruises Out of Rome, Italy

Many top cruise lines offer cruises from Rome. Sailing away on a Mediterranean cruise from Rome, Italy, is a dream come true when you embark on an adventure on any one of these cruise lines:

Rome Cruises Open Up a World of Cruise Travel Opportunities and Remarkable Destinations

When you book a Rome cruise, you're not only able to explore Italy and the Mediterranean; you're able to cruise all throughout the world. Sailing on cruises out of Rome, Italy, and choosing this beautiful, historical city as your departure port leaves you with so many places to explore, including:

Book cruises that leave from Italy today and you can lock in the best possible rate with CruiseDirect. With exciting extras and the lowest prices online, guaranteed, CruiseDirect is the best place to look for affordable cruises from Rome, Italy. Just ask any of our more than half a million customers! With free holds and low monthly cruise payment plans powered by Uplift, there's no better place online to buy tickets for Rome cruises.