Trevi Fountain

Trevi Fountain

Gardens of Vatican City

Gardens of Vatican City

Roman Forum

Roman Forum

Rome Colosseum

Rome Colosseum

Rome Skyline

Rome Skyline

San Pietro

San Pietro

Sistine Chapel

Sistine Chapel

Sistine Chapel

Sistine Chapel

Sistine Hall

Sistine Hall

The Sistine Hall of the Vatican Library

The Sistine Hall of the Vatican Library

Trevi Fountain

Trevi Fountain

Vatican Museum

Vatican Museum

Vatican Museum Staircase

Vatican Museum Staircase

View of Rome from the Vatican

View of Rome from the Vatican

Cruises From Rome: Your Gateway to Mediterranean Adventures

If Rome, Italy, isn't on your cruise vacation bucket list, you've either already been or simply forgotten to add it. Italy's capital city is a cultural destination with endless historical sites. It was once the center of the Roman Empire, and the unique history, captivating art, and architectural wonders you'll find here are well worth the trip. Rome is a great departure port for a cruise vacation, and at CruiseDirect, we have the best prices on scores of itineraries that begin in this beautiful city.

Every cruise from Rome should be bookended by sightseeing around the city. Visit the Vatican Museums, the Roman Forum, the Colosseum, the Pantheon, and St. Peter's Basilica. Art history lovers will find that time stops when they are standing underneath Michelangelo's Sistine Chapel ceiling! Rome's culinary scene is world-class, too, and the vibrant nightlife is also not to be missed, with live music and dance clubs found all throughout the city. Book cruises from Rome at the best price online and discover why they call it the Eternal City before you set sail!


 

  • Destination Port 1 Airport
  • Destination port 2 Departure port

Hotels In Rome

Anantara Palazzo Naiadi Rome Hotel a Leading Hotel of The World Hotel Image
Anantara Palazzo Naiadi Rome Hotel a Leading Hotel of The World

Dharma Luxury Hotel Hotel Image
Dharma Luxury Hotel

The St. Regis Rome Hotel Image
The St. Regis Rome

Cruise Lines Dec 25 Jan 26 Feb 26 Mar 26 Apr 26 May 26 Jun 26 Jul 26 Aug 26 Sep 26 Oct 26 Nov 26
Atlas Ocean Voyages               $5,849   $4,469    
Carnival Cruise Line                   $1,254 $1,049 $1,049
Celebrity Cruises         $1,599 $1,398 $1,099 $1,299 $1,299 $1,500 $1,218 $1,072
Costa $338 $188 $679 $589 $749 $519 $690 $1,260 $1,272 $1,090 $853 $657
Crystal Cruises                 $6,800 $6,400    
Cunard Line             $999 $899 $1,069 $895 $1,169  
Disney Cruise Line             $3,986          
Explora Journeys           $5,310 $5,320 $4,685 $4,685 $5,600 $5,935  
Holland America Line           $1,999 $1,196 $1,369 $1,319      
MSC Cruises $133 $462 $637 $538 $299 $801 $889 $1,001 $1,043 $924 $178 $956
Norwegian Cruise Line       $929   $949 $1,009 $1,059 $957 $929 $889 $1,289
Oceania Cruises         $4,999 $2,649 $1,980 $2,842 $2,160 $2,440 $1,890 $1,700
Princess Cruises       $811 $537 $849 $1,055 $1,105 $1,079 $1,209 $953 $1,006
Regent Seven Seas         $8,299 $6,449   $9,399   $9,600 $7,049 $7,599
Royal Caribbean Cruises         $2,408 $1,193 $1,172 $1,289 $1,194 $1,131 $1,132  
Seabourn Cruise Line                       $8,498
Silversea Cruises   $4,450 $3,950 $5,750   $5,000 $6,400 $7,000 $3,700 $10,300 $6,300 $6,100
Viking Ocean Cruises $3,699 $2,999 $3,499 $3,799 $5,299 $4,499 $3,999 $3,599 $4,299 $4,999 $4,799 $2,999
Virgin Voyages           $1,710     $1,791      
Windstar $3,644 $1,406 $1,406 $3,658 $3,781 $1,307   $3,217 $3,435 $3,334 $2,735  

Monthly Weather Averages

The graph that represents the temperature in fahrenheit
month graph
The graph that represents the precipitation rate forecast in inches
  • Temperature in Fahrenheit
  • Rain in Inches

Current Weather

Rome
56°F
Rain
Weather icon

Tuesday

57° 43°

Wednesday

56° 47°

Thursday

56° 47°

Friday

56° 46°

Cruise Lines That Offer Cruises Out of Rome, Italy

Many top cruise lines offer cruises from Rome. Sailing away on a Mediterranean cruise from Rome, Italy, is a dream come true when you embark on an adventure on any one of these cruise lines:

Rome Cruises Open Up a World of Cruise Travel Opportunities and Remarkable Destinations

When you book a Rome cruise, you're not only able to explore Italy and the Mediterranean; you're able to cruise all throughout the world. Sailing on cruises out of Rome, Italy, and choosing this beautiful, historical city as your departure port leaves you with so many places to explore, including:

Book cruises that leave from Italy today and you can lock in the best possible rate with CruiseDirect. With exciting extras and the lowest prices online, guaranteed, CruiseDirect is the best place to look for affordable cruises from Rome, Italy. Just ask any of our more than half a million customers! With free holds and low monthly cruise payment plans powered by Uplift, there's no better place online to buy tickets for Rome cruises.